徐华东
一、基本信息
姓名：徐华东
学历与学位：博士研究生
职称：讲师
职务：学术副院长
导师：硕导
E-mail：xuhuadong@hmc.edu.cn
二、个人简介
杭州医学院公共卫生学院学术副院长、硕士生导师，名古屋大学医学博士，北京大学公共卫生硕士。长期从事环境和职业健康风险与机制研究，主持国家自然科学基金等科研项目5项，以第一或通讯作者在Journal of Allergy and Clinical Immunology (一区IF = 14.2)等学术期刊发表论文二十余篇，参与编写《新型国家预防医学体系建立》、《中华职业医学(第二版)》、《呼吸系统毒理学》和《工程纳米材料职业健康与安全》，兼任中国毒理学会青年委员会委员、中国营养学会营养与免疫分会委员、浙江省生物医学学会理事以及浙江省毒理学会环境与生态毒理学专业委员会委员。
三、研究方向
环境和职业健康风险与机制研究。
四、主要科研成果
近五年第一/通讯作者论文
1. Xu H#, Tong K#, Iwasaki N, Ohgami N, Tazaki A, Kagawa T, Gao Y, Nishadhi DASM, Harusato A, Sakashita M, Ogi K, Fujieda S, Sumiya S, Iwasaki S, Kato M*. Alleviating effect of intranasal zinc on symptoms of allergic rhinitis. J Allergy Clin Immunol Glob, 2025, 100408.
2. Wang S, Song X, Su J, Hu B, Pan Y, Ding X, Liu X, Ding C, Chen T, Zhu X, Xu H*, Yan T*. Profiles and predictor of pesticide and metal mixtures in urine among solar greenhouse workers: findings from the measures of environment and the health outcomes study. J Occup Environ Med, 2025, 2025,10:1097.
3. Wang S, Sun W, Ding C, Zhou W, Zhang M*, Xu H*. The Role of Serum α-Klotho Levels in Preventing Hearing Impairment among Middle-aged and Older Adults: Insights from a Nationally Representative Sample. Front Aging Neurosci, 2024, 16, 1415494.
4. Xu H#, Wu F#, Ding C, Qin Y, Sun W, Feng L, Chen J, Jiang Z, Li Y, Xia H, Lou J*. The effect of the nucleolar protein ZNF385A on the ribosomal DNA copy number variation in response to Cr(VI)-induced DNA damage. Ecotoxicol Environ Saf, 2024, 284, 117018.
5. Sun W, Ding C, Jiang Z, Zheng X, Jiang J*, Xu H*. The impact of ambient air pollution on allergic rhinitis symptoms: a prospective follow-up study. Toxics, 2024, 12 (9), 663.
6. Xu H#, Shi L#, Feng L, Wu F, Chen J, Qin Y, Dong X, Jiang Z, Li Y, Xia H, Lou J*. Hexavalent chromium [Cr(VI)]-induced ribosomal DNA copy number variation and DNA damage responses and their associations with nucleolar protein HRAS in humans and cells. Environ Pollut, 2023, 331:121816.
7. Zhong Q, Sun W, Qin Y, Xu H*. Association of Dietary α-Carotene and β-Carotene Intake with Low Cognitive Performance in Older Adults: A Cross-Sectional Study from the National Health and Nutrition Examination Survey. Nutrients, 2023, 15, 239.
8. Zhong Q, Zhou W, Lin J, Sun W, Qin Y, Li X, Xu H*. Independent and Combined Associations of Blood Manganese, Cadmium and Lead Exposures with the Systemic Immune-Inflammation Index in Adults. Toxics, 2023, 11, 659.
9. Zhang J, Jiang J, Qin Y, Zhang Y, Wu Y, Xu H*. Systemic immune-inflammation index is associated with decreased bone mass density and osteoporosis in postmenopausal women but not in premenopausal women. Endocr Connect, 2023, 12(2):e220461.
10. Xu H*, Bo Y. Associations between pyrethroid exposure and serum sex steroid hormones in adults: Findings from a nationally representative sample. Chemosphere, 2022, 300:134591.
11. Xu H*, Mao Y, Hu Y, Xu B*. 2021. Association between exposure to polyfluoroalkyl chemicals and increased fractional exhaled nitric oxide in adults. Environ Res, 2021, 198:110450.
12. Xu H*, Mao Y, Xu B, Hu Y*. Low-level environmental lead and cadmium exposures and dyslipidemia in adults: Findings from the NHANES 2005–2016. J Trace Elem Med Biol, 2021, 63:126651.
13. Xu H, Ohgami N, Sakashita M, Ogi K, Hashimoto K, Tazaki A, Tong K, Aoki M, Fujieda S, Kato M*. Intranasal levels of lead as an exacerbation factor for allergic rhinitis in humans and mice. J Allergy Clin Immunol, 2021, 148(1):139-147.
14. Xu H*, Mao Y, Xu B*. 2020. Association between pyrethroid pesticide exposure and hearing loss in adolescents. Environ Res, 2020, 187:109640.
15. Xu H, Hashimoto K, Masao M, Azimi M D, Fayaz S H, Chen W, Hamajima N, Kato M*. High levels of boron promote anchorage-independent growth of nontumorigenic cells. Environ Pollut, 2020, 266:115094.
五、科研项目
1. 国家自然科学基金委员会, 青年科学基金项目, 2025.01-2027.12，主持；
2. 浙江省自然科学基金委员会, 探索项目, 2023.01-2025.12, 主持;
3. 浙江省教育厅，一般科研项目, 2022.09-2025.10, 主持;
4. 杭州医学院，基本科研业务费基础科研计划，2023.01-2025.12，主持；
5. 中国疾病预防控制中心化学污染与健康安全重点实验室, 开放基金项目, 2023.01-2023.12，主持。