一、基本信息

姓名：张静芸

学历与学位：博士研究生

导师：硕士生导师

职称：副研究员

E-mail：jingyunzhang1102@outlook.com

二、个人简介

学习研究背景交叉，具有南开大学统计学本科、兰州大学应用统计学硕士和中西医结合临床博士学位，并于浙江大学完成流行病与卫生统计学方向博士后工作。主要研究方向为衰老的分子流行病学。主持国家自然科学基金青年基金项目1项，参与国家自然科学基金面上项目2项，参与浙江省“尖兵”“领雁”研发公关计划项目1项，参与院级教改项目和交叉团队建设项目各1项。以第一/共同第一或者通讯/共同通讯作者在《BMC Medicine》、《Aging Cell》、《American Journal of Clinical Nutrition》等高影响力期刊发表SCI文章8篇，参与发表SCI 20余篇。担任中国老年医学会基础转化分会委员，担任SCI期刊《BMC Geriatrics》编委和《Phenomics》青年编委，担任《Aging cell》、《Frontiers in Public Health》等期刊审稿人。

三、研究方向

1）衰老分子流行病学；2）多组学纵向分析方法学

四、主要科研成果

1. Chen L., Fu J.^#, Jia X., Zhang L., Jin X., Wu S., Zhu B., Sun K., Fu D., Wang Y.^*, Liu Z. ^*, Li S. ^*, Zhang J. ^*. Immune cell subsets linking insomnia trajectories and incident cognitive impairment: a prospective cohort study. BMC Medicine. 2026. (中科院1区TOP)

2. Zhang J., Sun X.^#, Jia X., Sun B., Xu S., Zhang W., Liu Z.. Integrative multi-omics analysis reveals the critical role of the PBXIP1 gene in Alzheimer's disease. Aging cell. 2024;23(2):e14044.（中科院1区TOP）

3. Zhang J., Cao X.^#, Li X., Li X., Hao M., Xia Y., Huang H., Høj Jørgensen T. S., Agogo G. O., Wang L., Zhang X., Gao X., Liu Z.. Associations of Midlife Dietary Patterns with Incident Dementia and Brain Structure: Findings from the UK Biobank Study. The American journal of clinical nutrition. 2023;118(1):218-27.（中科院1区TOP）

4. Li X.^#, Cao X. ^#, Zhang J.^#, Fu J., Mohedaner M., Danzengzhuoga, Sun X., Yang G., Yang Z., Kuo C. L., Chen X., Cohen A. A., Liu Z.^*. Accelerated aging mediates the associations of unhealthy lifestyles with cardiovascular disease, cancer, and mortality. Journal of the American Geriatrics Society. 2024;72(1):181-93.（中科院2区TOP）

5. Zhang J., Cao X.^#, Chen C., He L., Ren Z., Xiao J., Han L., Wu X., Liu Z.^*. Predictive Utility of Mortality by Aging Measures at Different Hierarchical Levels and the Response to Modifiable Life Style Factors: Implications for Geroprotective Programs. Frontiers in medicine. 2022;9:831260.

6. Cao X.^#, Zhang J.^#, Ma C., Li X., Kuo C. L., Levine M. E., Hu G., Allore H., Chen X., Wu X.^*, Liu Z.^*. Life course traumas and cardiovascular disease-the mediating role of accelerated aging. Annals of the New York Academy of Sciences. 2022;1515(1):208-18.

7. Zhang J.^#, Yu S.^#, Zhao G., Jiang X.^*, Zhu Y. ^*, Liu Z.^*. Associations of chronic diarrheal symptoms and inflammatory bowel disease with sleep quality: A secondary analysis of NHANES 2005-2010. Frontiers in neurology. 2022;13:858439.

8. Zhang J.^#, Bing Z.^#, Yan P., Tian J., Shi X., Wang Y.^*, Yang K.^*. Identification of 17 mRNAs and a miRNA as an integrated prognostic signature for lung squamous cell carcinoma. The journal of gene medicine. 2019;21(8):e3105.